The RFU has confirmed it has been sounded out about the prospect of the Premier League club using the 82,000-capacity home of English rugby while Stamford Bridge is redeveloped.
Chelsea announced in June that they are looking at possible expansion plans for their stadium, although dates for any work have not been specified
It had previously been mooted that the club could seek out a permanent new home, however suitable London sites are in short supply.
The Scottish Rugby Union has allowed Murrayfield to be used for club football, with Celtic playing European games at the Edinburgh stadium earlier this year while Celtic Park and Hampden were tied up during the Commonwealth Games.
Twickenham has previously refused football teams permission to move in for short periods, with the then RFU chief executive Francis Baron saying in 2001, when Fulham were seeking a temporary home, that "we are not interested", citing difficulties with segregation of supporters along with traffic and policing issues.
The RFU said in a statement: "We are regularly contacted by a variety of organisations, within and outside sport, on a wide range of opportunities concerning use of what we believe is a world-class stadium
We have had an enquiry from Chelsea FC but have not had any discussions of any substance.
"While we don't comment on any specific confidential conversations, each request is taken on its merit, assessing a variety of factors, such as the effect on the pitch, availability, transport and local considerations and other important implications."
It is understood the RFU considers the enquiry to be a long way short of indicating that Chelsea have chosen Twickenham as the stadium they specifically would want to move to, should redevelopment work at Stamford Bridge necessitate a ground move.
There are thought to be other stadiums under consideration by the club owned by Russian billionaire Roman Abramovich
Tottenham have recently been linked with a move to play a number of games at Wembley in the 2017/18 season while their new home is built.
Source : PA
Source: PA