The Ivory Coast hitman is not even on the bench for the vital Premier League clash according to a close source, and looks as if he has played his last game for the Blues.
Drogba was sensationally dropped for the FA Cup tie in midweek and despite assurances from Ray Wilkins after that win over Southend, that Drogba remains firmly in Mr Scolari's plans, his absence will send shockwaves around SW6.
Drogba, 30, has played 191 games for Chelsea scoring 83 goals.
It looks as if Scolari's get-tough policy has resulted in sublime striker Drogba being the first casualty.
Results will determine if Scolari remains at Stamford Bridge next season.
Inter Milan and AC Milan will place bids for Drogba and he could be out of the Bridge by the end of next week.