The left-back did not play on Wednesday night as the Blues demolished Everton 4-1 in the Worthington Cup at Stamford Bridge.
But Babayaro now starts a three-match ban for his red card against Bolton, so Le Saux is expected to take his place.
Boudewijn Zenden, an unused substitute in midweek, could make his first appearance after a two-month ankle injury.
Albert Ferrer is a fortnight away from his comeback from a hamstring strain wh
ile Mikael Forssell will be back from his long-term knee injury in January.