The 33-year-old has enjoyed a glittering career in the Premier League since joining Chelsea in 2004 after just one season at Marseille.
Drogba has previously refused to rule out a return to Stade Velodrome towards the end of his career and he has just one year remaining on his contract at Stamford Bridge.
Reports suggest his future at Chelsea next season is uncertain as new manager Andre Villa-Boas looks to put his own stamp on the squad after replacing Carlo Ancelotti.
L'OM would be keen to have Drogba back at the club, but Labrune admits players would have to be sold in order to accommodate the Ivory Coast forward.
"The question is whether in terms of salary, I do not mean the transfer, Marseille have the means for four years to pay Didier Drogba," Labrune told La Provence.
"I answer 'yes'. But we cannot afford 11 Didier Drogbas.
"So is it possible? Yes, but in the case of departures."
Source: Team Talk
Source: Team Talk